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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MKI67IP All Species: 4.55
Human Site: Y143 Identified Species: 9.09
UniProt: Q9BYG3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.45
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYG3 NP_115766.3 293 34222 Y143 I P F K Q P S Y P S V K R Y N
Chimpanzee Pan troglodytes XP_515769 261 30438 R121 V K R Y N R N R T L T Q K L R
Rhesus Macaque Macaca mulatta XP_001085690 293 34043 H143 I P F K Q P S H P S V K R Y N
Dog Lupus familis XP_533319 297 34265 Y143 I P F K K P S Y P A V K R Y N
Cat Felis silvestris
Mouse Mus musculus Q91VE6 317 36247 F145 A L F H R P S F P A V K R Y N
Rat Rattus norvegicus Q5RJM0 271 31333 Q132 V H K D L F N Q C N V P F H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519520 250 28510 K119 R T D K Q K L K M K M R L E S
Chicken Gallus gallus XP_422088 277 31398 A128 M P P E R V H A N L F K N S E
Frog Xenopus laevis Q7SYS2 278 32306 R125 T P E K V H P R L F I G C N T
Zebra Danio Brachydanio rerio Q8JIY8 269 30081 V132 K V H E K L F V G S I A G F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002316513 217 25279 R86 F G T I K R L R I A R N K K T
Maize Zea mays NP_001148652 215 24686 R84 F G D I K R L R I A R N R K T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 94.1 73.7 N.A. 56.7 58 N.A. 36.1 50.1 40.6 46 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.7 96.9 84.8 N.A. 71.9 73.7 N.A. 50.5 65.1 55.9 61.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 86.6 N.A. 60 6.6 N.A. 13.3 13.3 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 80 33.3 N.A. 33.3 33.3 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 27.6 26.6 N.A. N.A. N.A. N.A.
Protein Similarity: 46 43.3 N.A. N.A. N.A. N.A.
P-Site Identity: 0 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 20 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 9 0 34 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % C
% Asp: 0 0 17 9 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 9 17 0 0 0 0 0 0 0 0 0 9 9 % E
% Phe: 17 0 34 0 0 9 9 9 0 9 9 0 9 9 0 % F
% Gly: 0 17 0 0 0 0 0 0 9 0 0 9 9 0 0 % G
% His: 0 9 9 9 0 9 9 9 0 0 0 0 0 9 0 % H
% Ile: 25 0 0 17 0 0 0 0 17 0 17 0 0 0 0 % I
% Lys: 9 9 9 42 34 9 0 9 0 9 0 42 17 17 9 % K
% Leu: 0 9 0 0 9 9 25 0 9 17 0 0 9 9 0 % L
% Met: 9 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 17 0 9 9 0 17 9 9 34 % N
% Pro: 0 42 9 0 0 34 9 0 34 0 0 9 0 0 9 % P
% Gln: 0 0 0 0 25 0 0 9 0 0 0 9 0 0 0 % Q
% Arg: 9 0 9 0 17 25 0 34 0 0 17 9 42 0 9 % R
% Ser: 0 0 0 0 0 0 34 0 0 25 0 0 0 9 9 % S
% Thr: 9 9 9 0 0 0 0 0 9 0 9 0 0 0 25 % T
% Val: 17 9 0 0 9 9 0 9 0 0 42 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 17 0 0 0 0 0 34 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _